Delivering the next generation of digital mental healthcare

Eight Billion Minds is a new digital therapeutics program from Ieso Digital Health with a vision to remove barriers to mental healthcare for millions of people around the world by delivering efficacious and regulated digital therapeutics for prescription use.

1 in 4adults

experience at least 1 diagnosable mental health problem in any year (1).


expected global cost 2010-2030 as a result of inaction to mental illness (2).


of real-world data from Ieso’s internet-enabled CBT platform (3).

By applying deep learning and clinical data science to hundreds of thousands of hours of real-world therapy data, Eight Billion Minds is determining what really works to help patients get better. Eight Billion Minds is developing new technology to deliver accessible and personalised psychological therapy on a global scale.

News & Views

TEDxNatick Talk: Artificial Intelligence Meets Mental Health Therapy

In January our Chief Science & Strategy Officer, Andy Blackwell, participated in the TEDxNatick Talk, where he addressed an 800 strong audience on why harnessing the power of deep learning and natural language processing, and applying it to real world clinical data, will allow for more personalized and improved mental healthcare treatments.


TEDMED 2020 kicks off in Boston today, running until March 4th, and designed to bring the entire TEDMED community together including health leaders, clinicians, researchers, scientists, creators innovators and influencers. With this year’s theme being ‘Make Way for Wonder’, attendees get to hear about the power and possibilities that are propelling humanity forward, and can join inspiring TEDMED Talks live and in person, as well as have the opportunity to attend inspirational workshops, classes and meetups.

Decoding therapy to deliver the next wave of digital mental healthcare services

The words we speak and hear create our experiences. They impact our thoughts, behavior and the way we feel. Words are particularly important in psychotherapy, and what is said during treatment can help an individual heal. In our society today, 1 in 4 adults experience at least one diagnosable mental health problem in any one year – but it often goes undetected and untreated, because people don’t necessarily deal with their symptoms or have easy access to care. For those who do receive treatment in the developed world, there is a shortfall in the quality and rate of improvement in care. This is because the methods for measuring the treatments delivered, as well as understanding the impact of the words uttered during therapy, has been lacking… until now.

2020 Will Be the Year of Real World Evidence, Predicts Ieso Digital Health

Ieso Digital Health, a leader in internet-enabled cognitive behavioural therapy (ie-CBT) and an innovator in digital therapeutics through its programme Eight Billion Minds, has predicted two big trends in digital healthcare for 2020. Emerging from developments in artificial intelligence and access to large scale real world data, Ieso explains why these trends could be game changers for the healthcare industry not just this year but over the next decade.

Ieso Hits Major Milestones in 2019

Ieso Digital Health, a leader in internet-enabled cognitive behavioural therapy (ie-CBT), is pleased to announce a momentous 2019, with many significant milestones met. Having been crowned business of the year at the Business Weekly awards and joining the Future Fifty Cohort early on in the year, Ieso went on to launch its DTx programme, Eight Billion Minds, in September to realise its vision to remove barriers in mental healthcare for millions of people globally. That same month, Ieso expanded its ie-CBT service to include Step 2 therapy to help address the 76.6 % of NHS IAPT (Increasing Access to Psychological Therapies) referrals needing low intensity mental health treatment. The service will be fully available to all NHS Clinical Commissioning Groups (CCGs) from January 2020.

Ieso Launches Clinical Research Trial to Treat Comorbid Depression and Anxiety in Patients with Type 2 Diabetes

Ieso to treat approximately 500 patients with tailored, online cognitive behavioural therapy to measure the effects of treatment Ieso Digital Health, a leader in internet-enabled cognitive behavioural therapy (ie-CBT), today announced its clinical trial to measure the effects of online, diabetes-focused CBT intervention on the mental health outcomes of patients with type 2 diabetes. Studies have found that mental health issues amongst those diagnosed with diabetes are far greater than for those without diabetes, with 25% reported to live with depression and 40% with anxiety . This study will help Ieso understand more about whether treating a mental health condition in the context of diabetes has a positive impact on mental wellbeing and subsequently diabetes management for patients.

Q&A: Ieso Digital Health’s SVP of AI on digital therapeutics and the new Eight Billion Minds project

The digital therapeutics field has attracted the interest of major players in the healthcare industry lately, from big pharma to the NHS. But there is debate among stakeholders around issues including reimbursement, regulation and business models that work. The space, however, continues to grow, and Cambridge-headquartered Ieso Digital Health unveiled earlier this year plans to build an autonomous digital therapeutic through its new Eight Billion Minds research project. Last week, MobiHealthNews caught up with Valentin Tablan, SVP of AI at the British mental health startup, to find out his thoughts on the current state of the digital therapeutics space and the new initiative.

How technology can be used to help mental health therapy

Ieso’s senior VP for artificial intelligence, Valentin Tablan, talks about the challenges of adopting technology in mental health and how things are changing through Ieso’s Eight Billion Minds program. Compared to physical medicine, mental health has traditionally been slow in its adoption of technology. There are multiple reasons for this, some psychological, some organisational, and some technological. Physical medicine has seen a lot of progress in the last century as science and technology advances have led to better understanding of diseases and patients. CAT and MRI scanners, and advanced lab tests make it easier to diagnose, treat and design personalised interventions for medical conditions. Mental health lags well behind, and still relies mainly on the skills and intuitions of practitioners, unaided by technology. One possible reason for this is that a large part of the information relevant to the treatment of mental health conditions is only available as natural language communication. Historically, we have focused less on how to objectively analyse this type of data than, for example, blood chemistry.

Ieso plots mental healthcare by AI with launch of Eight Billion Minds

Ieso Digital Health is aiming to build the next generation of mental healthcare by creating autonomous artificial intelligence-powered tools for patients. The Cambridge company has launched Eight Billion Minds, a new digital therapeutics program, to address the global shortages of therapists. Using deep learning models and natural language processing, the program is analysing real-world data from more than 200,000 therapy hours.

Ieso launches Eight Billion Minds programme to address unmet mental health needs

Ieso Digital Health has launched Eight Billion Minds, a new digital therapeutics programme aimed at addressing the global and regional shortages of mental health therapists. The campaign is building the next generation of mental healthcare based on analysis of high-volume, real-world clinical data from Ieso’s IECBT platform, ThinkWell, with a vision to making mental health treatments accessible for all.

Ieso launches Eight Billion Minds to address unmet global mental health needs

New digital therapeutics program to exploit major scientific discoveries from deep learning analysis of 200,000 hours of patient therapy Ieso Digital Health, a leader in internet-enabled cognitive behavioural therapy (IECBT), today launches Eight Billion Minds™, a new digital therapeutics program aiming to address the global and regional shortages of mental health therapists. Eight Billion Minds is building the next generation of mental healthcare based on analysis of high volume, real-world clinical data from Ieso’s IECBT platform, ThinkWell™, with a vision to make mental health treatments accessible for all. Combining practical knowledge of delivering differentiated clinical outcomes with the application of deep learning to hundreds of thousands of hours of therapy, the company has decoded what works in real-world clinical settings and plans to use new technology to distribute highly personalized therapies on a scale that is just not possible in 1:1 delivery.

New Ieso Digital Health study uses deep learning to reveal the features of psychotherapy that are related to patient improvement

Ieso Digital Health, a leader in internet-enabled cognitive behavioural therapy (ie-CBT), today announced the publication of new research which applied deep learning to large-scale clinical data to understand what aspects of psychotherapy content are associated with clinical outcomes. The paper ‘Quantifying the association between psychotherapy content and clinical outcomes using deep learning’, is published in JAMA Psychiatry, a peer-reviewed and highly-cited journal globally with more than 4.8 million article views and downloads annually.

Science & Data

Data-driven insights into effective therapy

How can new technology accelerate the development and delivery of digital therapeutics for mental health conditions?

Due to a global scarcity of therapists, the 1:1 therapy model faces limitations, with millions of people worldwide unable to access mental health treatment. Care quality and patient outcomes are often left unmeasured, with the therapy being delivered only as good as the individual therapist delivering the care.

Eight Billion Minds is addressing these issues and changing the future of how therapy is delivered around the world by using deep learning and data science, applied to its own unique data set, to understand what aspects of therapy really work.

So how do we do this?

1: Capture large volumes of therapy data from Ieso’s internet-enabled cognitive behavioural therapy (ie-CBT) service platform.

2: Apply deep learning, natural language processing (NLP) and clinical science to gain understanding of therapy-related language and what aspects of psychotherapy are most effective, for better targeted interventions.

3: By learning what works in real-world clinical settings, create new clinically engaging and effective digital therapeutics models to address unmet mental health needs which are scalable and autonomous.

4: Share new knowledge to services and clinicians to improve engagement and efficacy of traditional therapy.

Eight Billion Minds is the only company with the data to show which components of therapy are most effective for different types of patient. By learning from the best therapists, Ieso has the ability to improve recovery rates with its ie-CBT tool, and is now taking these learnings to develop scalable digital treatments within Eight Billion Minds to remove barriers to quality mental healthcare globally.

Ieso’s recovery rates surpass normal targets.
Recovery rates consistently improve in consecutive cohorts of 300 patients, which were used in order to control for the reliability of each measure of recovery.

How we use patient data for research

As the use of real world data grows, so does the ethical responsibility of those accessing and using it. We take seriously our responsibility to look after the data of our patients and clinicians, and have robust processes in place to safeguard their privacy, and to ensure data security. We also believe that it is our responsibility to make purposeful use of de-identified data in the pursuit of new and better treatments in the future. Our researchers work in close collaboration with clinician focus groups and a consumer advisory group to ensure the work that we are doing is always meaningful. You can watch a short video about how we use data here.

The Eight Billion Minds research programme uses de-identified treatment data from Ieso Digital Health’s ‘Thinkwell’ Platform. Patients signing up for treatment with the Thinkwell service receive the information here about how we use their data as part of the registration process. When patients sign up for treatment, we gather the information necessary to meet NHS quality oversight requirements (see IAPT minimum data set) and in order to conduct the important research of the Eight Billion Minds programme and other research to understand what works in CBT and further improve treatment, recovery rates and access.

We believe in transparency. We report outcomes for every patient we treat to NHS Digital, who make these statistics publicly available, and we routinely publish our findings in scientific journals. Our research publications report statistics, patterns, and conclusions – never individual treatments or conditions.

You can read Ieso’s full privacy policy here.


Passionate about improving access to mental health therapy

Dr Nigel Pitchford

Chief Executive Officer

Nigel became CEO of Ieso Digital Health in March 2019, having previously been the Chief Investment Officer and a group board director for Touchstone Innovations plc. Nigel led the team that created Eight Billion Minds, and is highly-regarded within the UK life sciences community, bringing significant fundraising, strategic and operational experience to the company.

Dr Andy Blackwell

Group Chief Science and Strategy Officer

At Ieso Digital Health, Andy’s principle role is to develop and implement a global science and technology strategy to complement the commercial vision of the company. As one of the leads in the development of Eight Billion Minds at Ieso, Andy has been instrumental in creating a business focused on using available real-world therapy data to address the unmet needs in mental health.

Sarah Bateup

Chief Clinical Officer

Sarah is a BABCP (British Association of Behavioural & Cognitive Psychotherapists) accredited cognitive behavioral therapist, and has delivered over 27,000 hours of cognitive behavioral therapy (CBT) to people across the UK. Sarah is responsible for all clinical management at Ieso, including therapist supervision and quality monitoring, She has been instrumental in analysing the data which will be used by Eight Billion Minds.

Dr Valentin Tablan

Chief Artificial Intelligence Officer

Valentin has spent 20 years in the field of Natural Language Processing, Knowledge Representation, and Artificial Intelligence. As SVP AI, at Ieso, Valentin and his team are responsible for applying advanced deep learning techniques to Ieso’s vast data set to determine which evidence-based therapy interventions are most effective. Under his leadership, Ieso has created the industry’s first AI-enabled tools that augment real-world data to increase quality and improve clinical outcomes.

Dr Jennifer Gentile

Senior VP, US Clinical Operations

Jennifer is a leader in the telehealth industry who provides leadership for US clinical operations and quality, and plays a key role in business and product development. She is responsible for ensuring that patients receive the highest quality care delivered by highly trained therapists supported by AI Therapist Assistants. Dr. Gentile works with key opinion leaders and stakeholders to secure success in the US healthcare marketplace.

Kate Woolland

Senior VP, Corporate Development

Kate leads corporate strategy, strategic sales, commercial partnerships and acquisitions, and is driving market access and commercialization strategies for Eight Billion Minds. She has particular expertise in working with senior stakeholders across multiple organisations to drive innovation and change in health systems.


Deep learning study reveals psychotherapy features related to patient improvement

Ieso Digital Health applies deep learning to large-scale clinical data to understand what aspects of psychotherapy content are associated with clinical outcomes. This study demonstrates the potential of what can be learnt when using real-world data and what could be achieved when these methods are applied to improve clinical practice and create digital therapeutics. The paper, ‘Quantifying the association between psychotherapy content and clinical outcomes using deep learning’, is published in JAMA Psychiatry, a peer-reviewed and highly-cited journal globally with more than 4.8 million article views and downloads annually.

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  1. Global Mental Health Commission
  2. Global Health Observatory Data Repository
  3. Ieso Digital Health dataset. Ieso applies organisational measures to ensure appropriate security and confidentiality of data, and provides transparency via the privacy notices.
  4. World Health Organization Fact Sheet on Depression